tert-butyl 3-bromophenylmethylcarbamate
Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester
CAS: 57598-34-2
Molecular Formula: C12H16BrNO2
tert-butyl 3-bromophenylmethylcarbamate - Names and Identifiers
tert-butyl 3-bromophenylmethylcarbamate - Physico-chemical Properties
| Molecular Formula | C12H16BrNO2 |
| Molar Mass | 286.16 |
tert-butyl 3-bromophenylmethylcarbamate - Introduction
Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester is an organic compound whose chemical formula is C12H15BrNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 296.16g/mol
-Melting Point: 78-80°C
-Boiling Point: 338-339°C
-Solubility: Soluble in some organic solvents, such as methanol and dichloromethane, insoluble in water
Use:
Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester is an important intermediate in organic synthesis. It is commonly used in drug synthesis and material science research and has the following main uses:
-Drug synthesis: It can be used to synthesize biologically active molecules, such as anti-cancer drugs, anti-viral drugs, etc.
-Materials Science: It can be used to prepare functional materials with special optical and electrical properties.
Preparation Method:
The preparation method of Carbamic acid, (3-bromophene) methyl-, 1,1-dimethylethyl ester can be realized by the following steps:
1. 3-Bromo-methylaniline is reacted with dimethylformamide to generate an amide compound.
2. Under alkaline conditions, the obtained amide compound is reacted with tert-butoxycarbonyl (BOC) ester to generate Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester.
3. Purify the product by crystallization or column chromatography.
Safety Information:
Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester are generally stable and not easily decomposed compounds under normal conditions. However, as a chemical, certain safety precautions are required:
-Avoid contact with skin and eyes: Wear appropriate personal protective equipment such as lab gloves and goggles when using.
-Avoid inhalation: Keep well ventilated during operation to avoid dust, smoke or gas.
-Storage Note: The compound should be stored in a dry, cool place, separated from oxygen and acid.
Due to the diversity of the nature and use of chemicals, it is recommended that before using or operating the compound, it is still necessary to refer to relevant literature and reliable chemical laboratory guidelines, and take corresponding safety measures.
Nature:
-Appearance: White crystalline solid
-Molecular weight: 296.16g/mol
-Melting Point: 78-80°C
-Boiling Point: 338-339°C
-Solubility: Soluble in some organic solvents, such as methanol and dichloromethane, insoluble in water
Use:
Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester is an important intermediate in organic synthesis. It is commonly used in drug synthesis and material science research and has the following main uses:
-Drug synthesis: It can be used to synthesize biologically active molecules, such as anti-cancer drugs, anti-viral drugs, etc.
-Materials Science: It can be used to prepare functional materials with special optical and electrical properties.
Preparation Method:
The preparation method of Carbamic acid, (3-bromophene) methyl-, 1,1-dimethylethyl ester can be realized by the following steps:
1. 3-Bromo-methylaniline is reacted with dimethylformamide to generate an amide compound.
2. Under alkaline conditions, the obtained amide compound is reacted with tert-butoxycarbonyl (BOC) ester to generate Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester.
3. Purify the product by crystallization or column chromatography.
Safety Information:
Carbamic acid, (3-bromophenyl)methyl-, 1,1-dimethylethyl ester are generally stable and not easily decomposed compounds under normal conditions. However, as a chemical, certain safety precautions are required:
-Avoid contact with skin and eyes: Wear appropriate personal protective equipment such as lab gloves and goggles when using.
-Avoid inhalation: Keep well ventilated during operation to avoid dust, smoke or gas.
-Storage Note: The compound should be stored in a dry, cool place, separated from oxygen and acid.
Due to the diversity of the nature and use of chemicals, it is recommended that before using or operating the compound, it is still necessary to refer to relevant literature and reliable chemical laboratory guidelines, and take corresponding safety measures.
Last Update：2024-04-09 20:45:29
